Description

2-(2-(2-Aminoethoxy)Ethoxy)Ethanol Hydrochloride is a versatile, water-soluble organic salt featuring a hydrophilic polyethylene glycol (PEG) spacer and a primary amine group. This compound matters as a critical bifunctional building block for the synthesis of complex molecules, enabling the introduction of both amine reactivity and PEG-like solubility. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and material science industries for creating drug conjugates, modifying surfaces, and developing advanced polymers.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing active pharmaceutical ingredients (APIs) and prodrugs, particularly in targeted cancer therapies.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles via its amine group.
• Polymer Chemistry: Serves as a monomer or chain extender in the production of specialty polyurethanes, polyamides, and other functional polymers.
• Surface Modification: Employed to create amine-functionalized surfaces on glass, metals, or polymers for subsequent chemical grafting.
• Crosslinking Agent: Utilized in the formulation of hydrogels and other crosslinked networks for biomedical applications.
• Ligand Synthesis: Building block for creating chelating agents and ligands used in catalysis or metal ion sequestration.

Basic Information

Product Name	2-(2-(2-Aminoethoxy)Ethoxy)Ethanol Hydrochloride
CAS No.	92505-84-5
Molecular Formula	C6H16ClNO3
Molecular Weight	185.65 g/mol
Synonyms	2,2'-(Ethylenedioxy)di(ethanamine) dihydrochloride; 8-Amino-3,6-dioxaoctan-1-ol hydrochloride; PEG3-amine hydrochloride; Tris(2-aminoethoxy)ethanol hydrochloride (incorrect but common); Amino-PEG3-alcohol hydrochloride; 2-[2-(2-Aminoethoxy)ethoxy]ethanol hydrochloride; 3,6-Dioxa-8-aminooctan-1-ol hydrochloride; O2O'-Bis(2-aminoethyl)triethylene glycol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-(2-Aminoethoxy)Ethoxy)Ethanol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.