Description

Z-D-Tyr(Bzl)-Oh CAS NO 92455-53-3 is a protected derivative of the amino acid tyrosine, specifically designed for use in peptide synthesis. This compound is a critical building block for researchers and manufacturers developing peptide-based pharmaceuticals and biochemical tools. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the controlled construction of complex peptide sequences where the tyrosine side chain must be selectively protected and deprotected.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptides on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for producing custom peptides and small protein fragments.
• Pharmaceutical Intermediate: Serves as a protected precursor in the research and development of therapeutic peptides targeting various diseases.
• Bioconjugation and Labeling: The protected benzyl (Bzl) group allows for specific modification of the peptide backbone at a later synthetic stage.
• Biochemical Research: Employed in the study of enzyme-substrate interactions, receptor binding, and structure-activity relationships (SAR).
• Production of Peptide Libraries: Used in combinatorial chemistry to generate diverse arrays of peptides for high-throughput screening.

Basic Information

Product Name	Z-D-Tyr(Bzl)-Oh
CAS No.	92455-53-3
Molecular Formula	C24H23NO5
Molecular Weight	405.44 g/mol
Synonyms	N-Carbobenzoxy-D-tyrosine benzyl ester; Z-D-Tyrosine benzyl ester; Z-D-Tyr-OBzl; N-(Benzyloxycarbonyl)-D-tyrosine benzyl ester; D-Tyrosine, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester; (R)-2-((((Benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanoic acid; Benzyl N-[(benzyloxy)carbonyl]-D-tyrosinate
EINECS	Contact for details

Quality Control

Our Z-D-Tyr(Bzl)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0% D-isomer
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.