Description

6-Chloroquinolin-2(1H)-One is a versatile heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysis, and advanced polymers.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic pathways.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Chloroquinolin-2(1H)-One
CAS No.	92449-39-3
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	6-Chloro-2(1H)-quinolinone; 6-Chloro-1H-quinolin-2-one; 6-Chloro-2-hydroxyquinoline; 6-Chloro-2-quinolone; 2-Hydroxy-6-chloroquinoline; 6-Chloro-2-quinolinol; 6-Chlorocarbostyril
EINECS	Contact for details

Quality Control

Our 6-Chloroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.