Description

Sialyl Lewis A, Sodium Salt is a high-purity, biologically significant carbohydrate derivative, specifically a sialylated tetrasaccharide. This compound serves as a critical ligand for selectins, playing a fundamental role in cell-cell recognition and adhesion processes. It is an essential research tool and potential intermediate for scientists and manufacturers in the fields of glycobiology research, immunology, and pharmaceutical development, particularly for studies involving inflammation, cancer metastasis, and leukocyte trafficking.

Application

• Biomedical Research: Used as a standard, inhibitor, or substrate in studies of selectin-mediated cell adhesion, inflammation, and immune response pathways.
• Diagnostic Development: Serves as a key component or coating antigen in the development of diagnostic assays and biosensors for disease markers.
• Drug Discovery: Acts as a lead compound or intermediate for the synthesis of novel anti-inflammatory or anti-metastatic therapeutic agents targeting selectin interactions.
• Glycoengineering: Utilized as a building block for the chemoenzymatic synthesis of more complex glycoconjugates, glycoproteins, or neoglycopolymers.
• Cell Culture & Analysis: Applied in functional cell-based assays to study binding kinetics, signal transduction, and the role of specific carbohydrate epitopes.
• Academic & Industrial R&D: A vital reagent for universities, research institutes, and biotech companies exploring carbohydrate-protein interactions.

Basic Information

Product Name	Sialyl Lewis A, Sodium Salt
CAS No.	92448-22-1
Molecular Formula	C31H51N2NaO22
Molecular Weight	866.73 g/mol
Synonyms	Sialyl Lea; SLea; CA19-9 Antigen; Sialyl Lewisa Tetrasaccharide Sodium Salt; Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAcβ-; 5-N-Acetyl-α-neuraminosyl-(2→3)-β-D-galactopyranosyl-(1→3)-[α-L-fucopyranosyl-(1→4)]-2-acetamido-2-deoxy-β-D-glucopyranose Sodium Salt; Monosialyl Lewis A; Carbohydrate Antigen 19-9
EINECS	Contact for details

Quality Control

Every batch of Sialyl Lewis A, Sodium Salt is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (on dried basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.