Description

Cyclobutanecarboxylic Acid, 1-Amino-, Methyl Ester, Hydrochloride (9Ci) is a high-purity, protected amino acid derivative featuring a constrained cyclobutane ring system. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptidomimetics Research: Used to introduce conformationally restricted, non-natural amino acid motifs into peptide analogs to enhance stability and biological activity.
• Medicinal Chemistry: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Chemical Biology Probes: Employed in the development of labeled compounds and molecular probes for biochemical and cellular studies.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of target molecules.
• Academic Research: A valuable reagent for synthetic organic chemistry and methodology development in university and institutional labs.

Basic Information

Item	Details
Product Name	Cyclobutanecarboxylic Acid, 1-Amino-, Methyl Ester, Hydrochloride (9Ci)
CAS No.	92398-47-5
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	1-Aminocyclobutanecarboxylic Acid Methyl Ester Hydrochloride; Methyl 1-Aminocyclobutanecarboxylate Hydrochloride; 1-Amino-cyclobutanecarboxylic Acid Methyl Ester HCl; Methyl 1-Amino-1-cyclobutanecarboxylate Hydrochloride; (1-Aminocyclobutyl)carboxylic Acid Methyl Ester Hydrochloride; 1-ACBC Methyl Ester Hydrochloride; Cyclobutane-1-carboxylic Acid, 1-Amino-, Methyl Ester, Hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Amino-, Methyl Ester, Hydrochloride (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade materials for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.