Description

5-Hydroxynorbornane 2,6-Lactone is a specialized bicyclic lactone compound with a unique, rigid molecular framework. This structure makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with defined stereochemistry. It is primarily sought by research and development laboratories in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a building block for constructing complex, stereochemically defined molecules due to its rigid norbornane skeleton and functional handles.
• Fine Chemical Production: Acts as a precursor in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring specific three-dimensional architecture.
• Academic & Industrial Research: Employed in methodological studies and catalysis research focused on ring-opening reactions, lactone chemistry, and stereoselective transformations.
• Ligand and Catalyst Development: The hydroxyl and lactone functionalities can be modified to create novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	5-Hydroxynorbornane 2,6-Lactone
CAS No.	92343-46-9
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	5-Hydroxy-2,6-norbornanolactone; 2-Oxabicyclo[2.2.1]heptan-3-one, 5-hydroxy-; 5-Hydroxy-2-oxabicyclo[2.2.1]heptan-3-one; Norbornane lactone derivative; Bicyclic lactone intermediate
EINECS	Contact for details

Quality Control

Our 5-Hydroxynorbornane 2,6-Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.