Description

[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is a complex, high-value indole alkaloid derivative characterized by its unique isocyano and chloro-substituted polycyclic structure. This compound matters as a sophisticated chemical intermediate and research building block, offering significant utility in advanced synthetic chemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), exploring new therapeutic scaffolds, and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex, biologically active molecules and potential new drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and the exploration of novel indole-based pharmacophores for various therapeutic targets.
• Organic Synthesis: Acts as a versatile precursor for further chemical transformations, leveraging its reactive isocyano and chloro functional groups.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and in studies investigating alkaloid chemistry and biosynthesis.
• Specialty Fine Chemicals: Used in the production of high-purity, custom-synthesized compounds for advanced material science applications.

Basic Information

Item	Details
Product Name	[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole
CAS No.	92219-95-9
Molecular Formula	C22H27ClN2
Molecular Weight	354.92 g/mol
Synonyms	(-)-8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,6,6aα,7,8,9,10,10aα-octahydronaphtho[1,2,3-cd]indole; 8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,3,6,6a,7,8,9,10,10a,10b-decahydronaphtho[1,2,3-cd]indole; 92219-95-9; Indole alkaloid derivative; Isocyanoterpene indole derivative.
EINECS	Contact for details

Quality Control

Our [6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.