Description

5-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Ol is a versatile brominated tetralin derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a hydroxyl group on a partially saturated naphthalene core, makes it valuable for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of central nervous system (CNS) active drugs, dopamine receptor ligands, and other therapeutic agents.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Material Science: Monomer or precursor for specialty polymers and liquid crystals where the bromine atom facilitates further functionalization.
• Academic & R&D: Valuable reagent in methodological chemistry research, particularly in studies involving stereoselective synthesis, cross-coupling reactions, and ring-forming transformations.
• Fine Chemical Synthesis: Intermediate for producing dyes, pigments, and other high-value specialty chemicals requiring a tetralin-based scaffold.

Basic Information

Product Name	5-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Ol
CAS No.	92013-31-5
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	5-Bromo-1-tetralol; 5-Bromo-1,2,3,4-tetrahydro-1-naphthol; 1-Hydroxy-5-bromo-1,2,3,4-tetrahydronaphthalene; 5-Bromo-α-tetralol; (5-Bromo-3,4-dihydronaphthalen-1(2H)-yl)methanol; 5-Bromotetralin-1-ol; 1(2H)-Naphthalenone, 5-bromo-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR, and IR for structural confirmation, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity	Contact for details
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.