Description

4,5-Dimethoxy-2-Nitrobenzyl Alcohol is a specialized aromatic nitro compound featuring a benzyl alcohol core substituted with dimethoxy and nitro groups. This unique structure makes it a valuable photo-labile protecting group precursor and a versatile chemical building block for advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel compounds and light-responsive systems.

Application

• Photoremovable Protecting Group (PPG) Synthesis: A key intermediate for preparing "caged" compounds, where it acts as a precursor to photolabile protecting groups for carboxylic acids, phosphates, and other functional groups, enabling precise spatiotemporal control in biological and chemical studies.
• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring light-sensitive or selectively deprotectable motifs.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, and plant growth regulators where its nitro and dimethoxy functionalities can be leveraged for bioactivity or as a synthetic handle.
• Material Science & Polymer Chemistry: Employed in the synthesis of specialty monomers, photoinitiators, and functional polymers designed for advanced coatings, adhesives, or photoresponsive materials.
• Dye & Pigment Intermediate: Functions as a precursor in the synthesis of complex aromatic dyes, pigments, and optical brighteners due to its nitro-aromatic structure.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for investigating new photochemical reactions and mechanisms.

Basic Information

Product Name	4,5-Dimethoxy-2-Nitrobenzyl Alcohol
CAS No.	1016-58-6
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	2-Nitro-4,5-dimethoxybenzyl Alcohol; 4,5-Dimethoxy-2-nitrobenzenemethanol; 1-(Hydroxymethyl)-4,5-dimethoxy-2-nitrobenzene; (4,5-Dimethoxy-2-nitrophenyl)methanol; DNMB-OH; α-Hydroxy-4,5-dimethoxy-2-nitrotoluene
EINECS	Contact for details

Quality Control

Our 4,5-Dimethoxy-2-Nitrobenzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring suitability for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to strong light sources.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.