Description

4-Chloro-2,6-Bis(trifluoromethyl)quinoline is a high-value, multi-functional fluorinated heterocyclic building block. This compound matters for its unique structural features, combining a quinoline core with chloro and trifluoromethyl substituents, which impart significant electronic and steric properties critical for advanced material and pharmaceutical synthesis. It is primarily needed by research chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Acts as a building block for creating organic semiconductors, liquid crystals, and fluorinated polymers with unique optical and electronic properties.
• Catalyst & Ligand Development: The quinoline structure can be modified to create novel nitrogen-based ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.

Basic Information

Item	Details
Product Name	4-Chloro-2,6-Bis(trifluoromethyl)quinoline
CAS No.	91991-79-6
Molecular Formula	C₁₂H₄ClF₆N
Molecular Weight	311.61 g/mol
Synonyms	4-Chloro-2,6-bis(trifluoromethyl)quinoline; 2,6-Bis(trifluoromethyl)-4-chloroquinoline; 4-Chloro-2,6-di(trifluoromethyl)quinoline; Quinoline, 4-chloro-2,6-bis(trifluoromethyl)-; 91991-79-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,6-Bis(trifluoromethyl)quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.