Description

1(2H)-Naphthalenone, Octahydro-5-Hydroxy-8A-Methyl- CAS NO 91965-65-0 is a high-purity, functionalized octahydronaphthalenone derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its precise stereochemistry and hydroxyl functionality, which are critical for constructing complex molecular architectures with high enantiomeric purity. It is primarily needed by R&D and production teams in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of steroidal drugs, hormone analogs, and other complex therapeutic agents.
• Fragrance & Flavor Synthesis: Used in the production of high-value aroma chemicals and flavoring agents due to its complex, fused-ring structure.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral scaffold in catalytic systems for enantioselective reactions.
• Material Science: Investigated as a monomer or modifying agent for creating specialized polymers with unique thermal or optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in total synthesis and the exploration of new chemical spaces.

Basic Information

Product Name	1(2H)-Naphthalenone, Octahydro-5-Hydroxy-8A-Methyl-
CAS No.	91965-65-0
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	5-Hydroxy-8a-methyl-octahydro-1(2H)-naphthalenone; 8a-Methyl-octahydro-5-hydroxy-1(2H)-naphthalenone; Octahydro-5-hydroxy-8a-methyl-1(2H)-naphthalenone; 8a-Methyl-3,4,4a,5,6,7,8,8a-octahydro-1H-naphthalen-5-ol; 5-Hydroxy-8a-methyl-perhydronaphthalen-1-one; (8aR)-5-Hydroxy-8a-methyl-3,4,4a,5,6,7,8,8a-octahydro-1H-naphthalen-1-one; (8aS)-5-Hydroxy-8a-methyl-3,4,4a,5,6,7,8,8a-octahydro-1H-naphthalen-1-one
EINECS	Contact for details

Quality Control

Our 1(2H)-Naphthalenone, Octahydro-5-Hydroxy-8A-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (Enantiomer-specific grades available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.