Description

2-Chloro-N-[1-(4-chlorophenyl)ethyl]acetamide is a specialized chlorinated acetamide derivative with a defined stereogenic center, serving as a valuable synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking high-purity building blocks for synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial activity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, or plant growth regulators that leverage its chlorinated phenyl and acetamide motifs.
• Chiral Synthesis: Serves as a precursor or resolving agent in asymmetric synthesis due to the presence of a chiral center, enabling the production of enantiomerically pure compounds.
• Organic Chemistry Research: A versatile substrate for studying nucleophilic substitution reactions, amide bond formation, and cross-coupling methodologies in academic and industrial labs.
• Ligand and Catalyst Development: Potential use in the design and synthesis of novel ligands for metal-catalyzed reactions or organocatalysts.
• Material Science Precursor: May be employed in the synthesis of specialized polymers or organic electronic materials requiring specific chlorinated aromatic units.

Basic Information

Product Name	2-Chloro-N-[1-(4-chlorophenyl)ethyl]acetamide
CAS No.	91900-33-3
Molecular Formula	C10H11Cl2NO
Molecular Weight	232.11 g/mol
Synonyms	2-Chloro-N-[1-(4-chlorophenyl)ethyl]acetamide; N-(1-(4-Chlorophenyl)ethyl)-2-chloroacetamide; α-Chloro-N-(α-methyl-4-chlorobenzyl)acetamide; 2-Chloro-N-(1-(4-chlorophenyl)ethyl)acetamide; Acetamide, 2-chloro-N-[1-(4-chlorophenyl)ethyl]-; 91900-33-3; (S)- or (R)-2-Chloro-N-[1-(4-chlorophenyl)ethyl]acetamide (for enantiopure forms)
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[1-(4-chlorophenyl)ethyl]acetamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (if applicable), and identity confirmation via IR and NMR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure the material meets your specific research or process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.