Description

2,5-Dichloro-[1,8]Naphthyridine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its dual reactive chlorine sites and the electron-deficient naphthyridine core, making it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and enzyme functions.
• Custom Synthesis & Scale-up: A fundamental starting material for contract research organizations (CROs) and custom synthesis providers.

Basic Information

Product Name	2,5-Dichloro-[1,8]Naphthyridine
CAS No.	91870-15-4
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	2,5-Dichloro-1,8-naphthyridine; 1,8-Naphthyridine, 2,5-dichloro-; 2,5-Dichloro-1,8-naphthyridine; 2,5-Dichloro[1,8]naphthyridine; 2,5-Dichloro-1,8-naphthyridine (9CI); 2,5-Dichloro[1,8]naphthyridine; 2,5-Dichloro-1,8-naphthyridine (6CI,7CI,8CI)
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-[1,8]Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.