Description

3'-Sialyl Lewis A is a complex, biologically significant tetrasaccharide that serves as a critical ligand in cellular recognition processes. This compound is essential for research and development in glycobiology and immunology, where it is used to study and modulate selectin-mediated cell adhesion. It is primarily utilized by pharmaceutical researchers, diagnostic developers, and academic institutions focused on inflammation, cancer metastasis, and immune response pathways. Our supply ensures high purity and batch-to-batch consistency for reliable experimental results.

Application

• Biomedical Research: As a key tool for studying carbohydrate-protein interactions, particularly with E-selectin and P-selectin.
• Drug Discovery: Serving as a reference standard or starting material in the development of anti-inflammatory and anti-metastatic therapeutics.
• Diagnostic Development: Used in the design and calibration of assays targeting sialylated glycans for disease biomarker detection.
• Glycoengineering: A vital substrate or intermediate for the enzymatic or chemical synthesis of more complex glycoconjugates.
• Cell Biology Studies: Employed in vitro to investigate leukocyte rolling, adhesion, and signaling events on endothelial cells.
• Quality Control: Acting as an analytical standard for the characterization of biologics and biosimilars that feature similar glycan structures.

Basic Information

Product Name	3'-Sialyl Lewis A
CAS No.	91847-18-6
Molecular Formula	C31H52N2O23
Molecular Weight	820.75 g/mol
Synonyms	3'-Sialyl Lewis A; Sialyl Lewis A; SLea; CA19-9 Antigen; Carbohydrate Antigen 19-9; Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAc; 3'-Sialyllacto-N-fucopentaose II; SLex A; 3'-Sialyl-N-acetyllactosamine Fucosyl Oligosaccharide
EINECS	Contact for details

Quality Control

Every batch of 3'-Sialyl Lewis A is produced and analyzed under strict quality management protocols to ensure identity, purity, and performance. We provide comprehensive Certificates of Analysis (COA) detailing results from advanced analytical techniques including HPLC, NMR, and MS. Our quality system is designed to support research requiring high-purity biochemical standards, with documentation available to meet regulatory and publication standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.