Description

1,2-Dihydro-1,2-Dihydroxy-6-Nitrochrysene is a high-purity, specialized nitroaromatic compound of significant interest in advanced chemical research and development. This compound serves as a critical intermediate and reference standard for studying polycyclic aromatic hydrocarbon (PAH) metabolism, environmental fate, and toxicology. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical developers requiring precise and reliable materials for method validation and investigative studies.

Application

• Metabolite Standard: Used as a certified reference material (CRM) for the analysis of chrysene metabolites in environmental and biological samples.
• Toxicology Research: A key compound in studies investigating the metabolic activation pathways, DNA adduct formation, and carcinogenic mechanisms of nitro-PAHs.
• Environmental Analysis: Employed as an analytical standard in HPLC, GC-MS, and LC-MS methods for monitoring PAH transformation products in soil, water, and air particulates.
• Biochemical Studies: Utilized in enzymatic assays to study the activity of dihydrodiol dehydrogenases and other enzymes involved in PAH detoxification or activation.
• Pharmaceutical Intermediates: Serves as a sophisticated building block in the synthesis of complex molecules for pharmacological research.
• Quality Control: Acts as a purity standard for calibrating analytical equipment and validating testing protocols within quality control laboratories.

Basic Information

Product Name	1,2-Dihydro-1,2-Dihydroxy-6-Nitrochrysene
CAS No.	91828-72-7
Molecular Formula	C₁₈H₁₃NO₄
Molecular Weight	307.30 g/mol
Synonyms	6-Nitrochrysene-1,2-dihydrodiol; 1,2-Dihydroxy-1,2-dihydro-6-nitrochrysene; (+/-)-1,2-Dihydro-1,2-dihydroxy-6-nitrochrysene; 6-Nitrochrysene dihydrodiol; NSC 339586; Chrysene-1,2-diol, 6-nitro-; 1,2-Dihydroxy-6-nitro-1,2-dihydrochrysene
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-1,2-Dihydroxy-6-Nitrochrysene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, batch-to-batch consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.