Description

1-Oxa-3-Azaspiro[4.5]Decane-4-Carbonitrile,4-Methyl-2-Oxo-(7Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical precursor for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to create new libraries of bioactive compounds.

Application

This versatile spirocyclic nitrile is engineered for sophisticated synthetic applications, including:

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used for scaffold hopping and structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Agrochemical Development: Serves as a precursor in creating novel active ingredients for crop protection products with new modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring complex heterocyclic frameworks.

Basic Information

Product Name	1-Oxa-3-Azaspiro[4.5]Decane-4-Carbonitrile,4-Methyl-2-Oxo-(7Ci)
CAS No.	91761-08-9
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	4-Methyl-2-oxo-1-oxa-3-azaspiro[4.5]decane-4-carbonitrile; 1-Oxa-3-azaspiro[4.5]decane-4-carbonitrile, 4-methyl-2-oxo-; 4-Methyl-2-oxo-1-oxa-3-azaspiro[4.5]decane-4-carbonitrile (7CI); 4-Cyano-4-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decane; Spiro[1-oxa-3-azacyclopentane-4,1'-cyclohexane]-4-carbonitrile, 4-methyl-2-oxo-
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-3-Azaspiro[4.5]Decane-4-Carbonitrile,4-Methyl-2-Oxo-(7Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), physical data, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.