Description

Cyclobutanol, 1-Ethynyl-2-(2-Methyl-1-Propenyl)-, trans- (9Ci) is a specialized, high-purity organic compound featuring a unique cyclobutanol core functionalized with ethynyl and prenyl-like substituents. This compound matters as a versatile and valuable advanced pharmaceutical intermediate and key synthon for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates with complex cyclic structures.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Asymmetric Synthesis: The defined stereochemistry (trans-) makes it a valuable chiral precursor or auxiliary for stereoselective reactions.
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides with novel modes of action.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials due to its rigid, functionalized core.
• Academic & Institutional R&D: A valuable reagent for methodology development and exploring new organic reaction pathways in university and government laboratories.

Basic Information

Item	Details
Product Name	Cyclobutanol, 1-Ethynyl-2-(2-Methyl-1-Propenyl)-, trans- (9Ci)
CAS No.	91531-61-2
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	trans-1-Ethynyl-2-(2-methyl-1-propenyl)cyclobutanol; 1-Ethynyl-2-(2-methylprop-1-en-1-yl)cyclobutan-1-ol (trans-); (1R,2S)-1-Ethynyl-2-(2-methylprop-1-en-1-yl)cyclobutan-1-ol; (1S,2R)-1-Ethynyl-2-(2-methylprop-1-en-1-yl)cyclobutan-1-ol; NSC 405122; 1-Ethynyl-2-(2-methyl-1-propen-1-yl)cyclobutanol; Cyclobutanol, 1-ethynyl-2-(2-methyl-1-propenyl)-, trans-
EINECS	Contact for details

Quality Control

Our Cyclobutanol, 1-Ethynyl-2-(2-Methyl-1-Propenyl)-, trans- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring traceability and consistency for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept tightly sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.