Description

Tetrahydropyran-2-Methanol CAS NO 100-72-1 is a versatile heterocyclic alcohol and a valuable chemical intermediate in organic synthesis. Its unique structure, featuring both a cyclic ether (tetrahydropyran) and a primary alcohol functional group, makes it a crucial building block for creating more complex molecules. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its heterocyclic structure contributes to biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Polymer Modification: Employed to introduce functional groups into polymer chains, modifying properties like solubility, adhesion, and reactivity for specialty coatings and resins.
• Flavor and Fragrance Industry: Utilized as an intermediate in the synthesis of certain aroma chemicals and fragrance components.
• Organic Synthesis Research: A fundamental reagent in academic and industrial R&D for constructing complex molecular architectures, including natural product analogs.

Basic Information

Item	Detail
Product Name	Tetrahydropyran-2-Methanol
CAS No.	100-72-1
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	2-(Hydroxymethyl)tetrahydropyran; Tetrahydropyran-2-ylmethanol; Oxan-2-ylmethanol; 2-Tetrahydropyranylmethanol; THP-2-Methanol; 2-Hydroxymethyltetrahydropyran; α-(Hydroxymethyl)tetrahydropyran
EINECS	202-883-1

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production of Tetrahydropyran-2-Methanol adheres to current Good Manufacturing Practice (GMP) principles where applicable, ensuring batch-to-batch consistency and traceability. Every lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.455 - 1.465
Specific Gravity (20°C)	1.020 - 1.040

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.