Description

2-Bromo-2,3-Dihydro-4-Methyl-1H-Inden-1-One is a versatile brominated indanone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated structure makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce specific bromine functionality into their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive bromine site for further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to create complex, multi-substituted aromatic systems.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Bromo-2,3-Dihydro-4-Methyl-1H-Inden-1-One
CAS No.	91445-80-6
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	2-Bromo-4-methylindan-1-one; 2-Bromo-4-methyl-2,3-dihydro-1H-inden-1-one; 4-Methyl-2-bromoindan-1-one; 1H-Inden-1-one, 2-bromo-2,3-dihydro-4-methyl-; 2-Bromo-4-methyl-1-indanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,3-Dihydro-4-Methyl-1H-Inden-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.