Description

1-Azabicyclo[2.2.2]Octane, 3-Ethynyl- (9Ci) is a specialized bicyclic tertiary amine building block featuring a reactive ethynyl (acetylene) group. This compound is valued for its unique structural motif, which serves as a key scaffold in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a core structure in the development of new crop protection agents and herbicides.
• Material Science: Employed in the creation of advanced polymers and functional materials due to its rigid bicyclic structure and polymerizable ethynyl group.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tools to study biological systems via click chemistry reactions.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane, 3-Ethynyl- (9Ci)
CAS No.	91239-94-0
Molecular Formula	C9H13N
Molecular Weight	135.21 g/mol
Synonyms	3-Ethynyl-1-azabicyclo[2.2.2]octane; 3-Ethynylquinuclidine; 1-Azabicyclo[2.2.2]octane, 3-ethynyl-; 3-Ethynylquinuclidine; Quinuclidine, 3-ethynyl-; 3-Ethynyl-1-azoniabicyclo[2.2.2]octane (cationic form reference); Bicyclic tertiary amine alkyne
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane, 3-Ethynyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.