Description

4-tert-Butyl-3-Iodobenzoic Acid is a high-purity iodinated benzoic acid derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a sterically hindered tert-butyl group and a reactive iodine atom, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, where the iodine atom facilitates further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its aromatic and halogenated structure.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Item	Detail
Product Name	4-tert-Butyl-3-Iodobenzoic Acid
CAS No.	91131-72-5
Molecular Formula	C11H13IO2
Molecular Weight	304.13 g/mol
Synonyms	3-Iodo-4-tert-butylbenzoic Acid; 4-(1,1-Dimethylethyl)-3-iodobenzoic Acid; Benzoic acid, 4-(1,1-dimethylethyl)-3-iodo-; 4-tert-Butyl-3-iodobenzoic acid; 4-tert-Butyl-3-iodobenzoic acid CAS 91131-72-5; 3-Iodo-4-(tert-butyl)benzoic acid; 4-(tert-Butyl)-3-iodobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-tert-Butyl-3-Iodobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.