Description

D-[4-13C]Threose is a stable isotope-labeled analog of the monosaccharide D-threose, specifically enriched with carbon-13 at the 4-position. This compound is an essential tool for advanced metabolic and biochemical research, enabling precise tracking and quantification of carbohydrate pathways using techniques like NMR spectroscopy and mass spectrometry. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies engaged in isotope tracing studies, metabolic flux analysis, and the development of labeled standards for analytical applications.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in NMR and LC-MS studies to elucidate carbohydrate metabolism and glycolytic fluxes in biological systems.
• Biochemical Research: Serves as a key intermediate in the synthesis of isotopically labeled complex carbohydrates, nucleotides, and other bioactive molecules for research.
• Analytical Standard Development: Employed as a certified reference material (CRM) or internal standard for the accurate quantification of threose and related saccharides in mass spectrometry.
• Pharmaceutical R&D: Facilitates drug metabolism and pharmacokinetic (DMPK) studies for sugar-based pharmaceuticals by providing a distinguishable isotopic signature.
• Nutritional Science Studies: Applied in research investigating the metabolism of rare sugars and their physiological effects.

Basic Information

Product Name	D-[4-13C]Threose
CAS No.	90913-09-0
Molecular Formula	C313CH8O4
Molecular Weight	122.10 g/mol (for 13C1 labeled form)
Synonyms	(2R,3S)-2,3,4-Trihydroxybutanal-4-13C; D-Threose-4-13C; D-(-)-Threose-4-13C; [4-13C]-D-Threose; Isotopically labeled D-threose; 13C1-D-Threose; Carbon-13 labeled D-threose
EINECS	Contact for details

Quality Control

Every batch of D-[4-13C]Threose is produced and analyzed under strict quality protocols to ensure high isotopic and chemical purity. Our standard quality commitment includes verification of isotopic enrichment (typically ≥99 atom % 13C) and chemical purity by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic purity, identity, and specific tests for impurities. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.