Description

Serine, 2-Carboxyhydrazide, tert-Butyl Ester (7Ci) is a specialized, high-purity amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a protected serine hydrazide intermediate, enabling the precise construction of complex molecules like peptides and heterocycles. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce serine moieties with orthogonal protecting group strategies.
• Heterocyclic Chemistry: Serves as a precursor for the synthesis of various nitrogen-containing heterocycles, which are core structures in many agrochemicals and pharmaceuticals.
• Bioconjugation & Probe Development: Utilized in the design and synthesis of chemical probes, linkers, and bioconjugates for biochemical and diagnostic applications.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals for client projects.

Basic Information

Product Name	Serine, 2-Carboxyhydrazide, tert-Butyl Ester (7Ci)
CAS No.	90867-96-2
Molecular Formula	C8H17N3O4
Molecular Weight	219.24 g/mol
Synonyms	tert-Butyl 2-(hydrazinecarbonyl)amino-3-hydroxypropanoate; N2-(tert-Butoxycarbonyl)-L-serine hydrazide; (2S)-2-[[(tert-Butoxy)carbonyl]amino]-3-hydroxypropanehydrazide; Boc-Ser-NHNH2; Boc-L-serine hydrazide; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxypropanehydrazide; L-Serine, N2-[(1,1-dimethylethoxy)carbonyl]-, hydrazide
EINECS	Contact for details

Quality Control

Our Serine, 2-Carboxyhydrazide, tert-Butyl Ester (7Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.