Description

3-Hydroxy-1-Iodonaphthalene is a versatile iodinated naphthalene derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a reactive iodine atom with a phenolic hydroxyl group, makes it a valuable precursor for constructing complex molecules through cross-coupling and functional group transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing new active ingredients, as well as in materials science for creating specialized organic electronic components.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system and oncological pathways.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoconductive materials.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Fluorescent Probe Synthesis: Intermediate in the creation of naphthalene-based fluorescent dyes and sensors for biochemical assays.

Basic Information

Product Name	3-Hydroxy-1-Iodonaphthalene
CAS No.	90800-21-8
Molecular Formula	C₁₀H₇IO
Molecular Weight	270.07 g/mol
Synonyms	1-Iodo-3-hydroxynaphthalene; 3-Hydroxynaphthalen-1-yl iodide; 3-Hydroxy-1-iodonaphthalene; 1-Iodo-3-naphthol; 3-Iodo-1-naphthol (common misnomer); Naphthalen-1-ol, 3-iodo-; 90800-21-8 (CAS Registry)
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-1-Iodonaphthalene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.