Description

4-(1H-Imidazol-2-Yl)-Piperidine 2Hcl is a high-purity, versatile heterocyclic building block and pharmaceutical intermediate. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting the central nervous system. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Ligand Synthesis: Employed in the development of novel ligands for biological receptors and enzymes.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to introduce the imidazole-piperidine moiety into complex molecules.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry and its applications.

Basic Information

Product Name	4-(1H-Imidazol-2-Yl)-Piperidine 2Hcl
CAS No.	90747-46-9
Molecular Formula	C8H13N3 · 2HCl
Molecular Weight	240.13 g/mol (as free base: 151.21 g/mol)
Synonyms	4-(1H-Imidazol-2-yl)piperidine dihydrochloride; 2-(4-Piperidinyl)-1H-imidazole dihydrochloride; 4-(2-Imidazolyl)piperidine dihydrochloride; 4-(Imidazol-2-yl)piperidine 2HCl; 4-(1H-Imidazol-2-yl)piperidine hydrochloride (2:1); Piperidine, 4-(1H-imidazol-2-yl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(1H-Imidazol-2-Yl)-Piperidine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.