Description

3-(3-Amino-4-Hydroxy-Phenyl)-Propionic Acid is a versatile aromatic amino acid derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both an amino and a phenolic hydroxyl group on the phenyl ring attached to a propionic acid chain, makes it a valuable intermediate for creating complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Peptide Mimetic Synthesis: Used to incorporate constrained tyrosine-like structures into peptide chains to enhance stability and biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and high-performance pigments.
• Ligand for Metal Complexation: Utilized in the development of chelating agents and catalysts due to its phenolic and amino donor groups.
• Bioconjugation and Linker Chemistry: Employed in creating cross-linking agents and spacers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: Essential compound in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-(3-Amino-4-Hydroxy-Phenyl)-Propionic Acid
CAS No.	90717-66-1
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	3-(3-Amino-4-hydroxyphenyl)propanoic acid; 3-Amino-4-hydroxyhydrocinnamic acid; 4-Hydroxy-3-aminohydrocinnamic acid; 3-(3-Amino-4-hydroxy-phenyl)-propionic acid; 2-(3-Amino-4-hydroxyphenyl)ethanoic acid (tautomeric form); β-(3-Amino-4-hydroxyphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Amino-4-Hydroxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.