Description

4-Bromo-1-Methoxy-2-(Methylsulfonyl)Benzene is a high-purity, multi-functional aromatic sulfone building block essential for advanced organic synthesis. Its unique structure, featuring bromine, methoxy, and methylsulfonyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzene sulfone core.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and sulfone functionalities.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex molecular architectures in medicinal chemistry and chemical biology.

Basic Information

Product Name	4-Bromo-1-Methoxy-2-(Methylsulfonyl)Benzene
CAS No.	90531-99-0
Molecular Formula	C8H9BrO3S
Molecular Weight	265.13 g/mol
Synonyms	1-Bromo-4-Methoxy-2-(Methylsulfonyl)Benzene; 2-Bromo-5-Methoxybenzenesulfonyl Methane; 4-Bromo-2-(Methylsulfonyl)Anisole; 2-Methylsulfonyl-4-Bromoanisole; 90531-99-0; 4-Bromo-1-methoxy-2-(methylsulfonyl)-benzene; Benzene, 4-bromo-1-methoxy-2-(methylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methoxy-2-(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.