Description

8-Methoxy-5-Quinolinesulfonyl Chloride is a key sulfonyl chloride derivative used as a versatile building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the 8-methoxyquinoline-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemical intermediates. The product is supplied under strict quality control to ensure consistency and reliability for critical synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the quinoline scaffold contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex heterocyclic dyes and optical brighteners.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	8-Methoxy-5-Quinolinesulfonyl Chloride
CAS No.	90429-62-2
Molecular Formula	C10H8ClNO3S
Molecular Weight	257.69 g/mol
Synonyms	5-Quinolinesulfonyl chloride, 8-methoxy-; 8-Methoxyquinoline-5-sulfonyl chloride; 8-Methoxy-5-quinolinesulfonyl chloride; 90429-62-2; 8-Methoxyquinoline-5-sulphonyl chloride; 5-(Chlorosulfonyl)-8-methoxyquinoline; 8-Methoxy-5-sulfonylchloride quinoline
EINECS	Contact for details

Quality Control

Every batch of 8-Methoxy-5-Quinolinesulfonyl Chloride is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure compliance with high-purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.