Description

2-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-6,7-Dimethoxy-Quinolin-4-Amine is a complex heterocyclic organic compound featuring fused quinoline and isoquinoline moieties, making it a valuable intermediate for advanced chemical synthesis. This compound matters for its role as a key building block in the development of pharmacologically active molecules, particularly in medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to support the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Alkaloid Analog Synthesis: Employed in the preparation of synthetic analogs of natural tetrahydroisoquinoline alkaloids for biological evaluation.
• Ligand Development: Acts as a core structure for developing chelating agents or enzyme inhibitors in biochemical assays.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory organic synthesis and methodological studies.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing specialized, high-value chemical entities.

Basic Information

Product Name	2-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-6,7-Dimethoxy-Quinolin-4-Amine
CAS No.	90402-40-7
Molecular Formula	C22H25N3O4
Molecular Weight	395.45 g/mol
Synonyms	4-Amino-2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinoline; 2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine; 90402-40-7; Quinolin-4-amine, 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-; 6,7-Dimethoxy-2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-amine
EINECS	Contact for details

Quality Control

Our 2-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-6,7-Dimethoxy-Quinolin-4-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.