Description

n-Methyl-3-Fluorobenzylamine Hydrochloride is a high-purity organic salt building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its unique fluorinated benzylamine structure is essential. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorinated motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Serves as a precursor for various fluorinated fine chemicals and specialty materials used in electronics and advanced polymers.
• Bioconjugation and Probe Synthesis: Useful in life sciences research for creating fluorescent probes, biomarkers, and other bioconjugation reagents.
• Academic and Industrial R&D: A valuable reagent for method development and exploratory synthesis in both academic laboratories and corporate R&D divisions.

Basic Information

Product Name	n-Methyl-3-Fluorobenzylamine Hydrochloride
CAS No.	90389-40-5
Molecular Formula	C8H11FN • HCl
Molecular Weight	175.64 g/mol (Free base: 139.18 g/mol)
Synonyms	1-(3-Fluorophenyl)-N-methylmethanamine hydrochloride; 3-Fluoro-N-methylbenzylamine hydrochloride; (3-Fluorobenzyl)methylamine hydrochloride; N-Methyl-1-(3-fluorophenyl)methanamine hydrochloride; N-Methyl-3-fluorobenzylamine HCl; α-Methylamino-3-fluorotoluene hydrochloride; Benzenemethanamine, 3-fluoro-N-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-3-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.