Description

2-Chloro-4-Fluoro-3-Methylnitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture makes it an indispensable intermediate for creating complex molecules with targeted biological and chemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents enhance biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl structures.
• Organic Synthesis Building Block: Utilized in nucleophilic aromatic substitution and reduction reactions to introduce amino or other functional groups.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-Methylnitrobenzene
CAS No.	90292-62-9
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	1-Chloro-2-fluoro-5-methyl-4-nitrobenzene; 2-Chloro-4-fluoro-3-nitrotoluene; 3-Methyl-2-chloro-4-fluoronitrobenzene; Benzene, 2-chloro-4-fluoro-3-methyl-1-nitro-; 4-Fluoro-2-chloro-3-methylnitrobenzene; 2-Chloro-4-fluoro-3-nitrotoluene; 5-Methyl-2-chloro-4-fluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3-Methylnitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.