Description

Dimethyl 1-Methylcyclopropane-1,2-Dicarboxylate is a high-purity, versatile diester building block essential for advanced organic synthesis. This compound is valued for its strained cyclopropane ring, which serves as a key structural motif and reactive intermediate in the development of complex molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane pharmacophores for antiviral, anticancer, or central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the cyclopropane ring enhances biological activity and stability.
• Organic Synthesis Building Block: Serves as a versatile scaffold for [2+1] cycloaddition reactions, ring-opening polymerizations, and the preparation of complex natural product analogs in academic and industrial research.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs) due to its rigid, three-membered ring structure.
• Flavor & Fragrance Chemistry: Acts as a synthetic intermediate for creating unique musk compounds and other complex aroma chemicals.

Basic Information

Item	Details
Product Name	Dimethyl 1-Methylcyclopropane-1,2-Dicarboxylate
CAS No.	90200-11-6
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	1-Methylcyclopropane-1,2-dicarboxylic acid dimethyl ester; Dimethyl 1-methyl-1,2-cyclopropanedicarboxylate; 1-Methyl-1,2-cyclopropanedicarboxylic Acid Dimethyl Ester; Methyl 1-methylcyclopropane-1,2-dicarboxylate; 1-Methylcyclopropane-1,2-dicarboxylate dimethyl ester; (1-Methylcyclopropane-1,2-diyl)dimethyl dicarboxylate
EINECS	Contact for details

Quality Control

Our Dimethyl 1-Methylcyclopropane-1,2-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.