Description

(-)-Gossypol is the levo-rotatory enantiomer of the natural polyphenolic compound gossypol, isolated from cotton plants. This specific stereoisomer is of significant interest in biochemical and pharmaceutical research due to its distinct biological activity profile compared to its racemic or (+)-form. It is primarily utilized by research institutions and pharmaceutical developers investigating its potential therapeutic applications and unique mechanism of action.

Application

• Pharmaceutical Research & Development: Investigated as a lead compound for its potential anti-cancer, anti-viral, and anti-parasitic properties.
• Biochemical Studies: Used as a specific inhibitor or modulator in enzymatic and receptor-binding assays to study biological pathways.
• Reference Standard: Serves as a high-purity chromatographic standard for analytical method development and quality control in natural product analysis.
• Academic Research: Employed in universities and research institutes for studies in medicinal chemistry, stereochemistry, and plant-derived bioactive compounds.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* models to evaluate pharmacokinetics, toxicity, and efficacy of the (-)-enantiomer.

Basic Information

Product Name	(-)-Gossypol
CAS No.	90141-22-3
Molecular Formula	C30H30O8
Molecular Weight	518.56 g/mol
Synonyms	(-)-Gossypol; Levogossypol; (1R,1'R)-Gossypol; (R)-Gossypol; Gossypol, levo-; 2,2'-Binaphthalene-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-, (1R,1'R)-; AT-101 (enantiomer specific)
EINECS	Contact for details

Quality Control

Our (-)-Gossypol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical identity, and impurity profile. We support research and development with material suitable for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (-)-enantiomer
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.