Description

(S)-o-Isopropylidene Glycerol Mesylate is a high-purity chiral building block and key pharmaceutical intermediate. This compound matters for its critical role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing and producing advanced chiral molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure drugs, including antiviral agents, β-blockers, and other cardiovascular medications.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in various asymmetric catalytic reactions and total synthesis projects.
• Nucleoside & Nucleotide Chemistry: Employed in the preparation of modified nucleosides and nucleotides for antiviral and anticancer research.
• Polymer Chemistry: Acts as a monomer or co-monomer for creating specialty polymers with specific chiral or functional properties.
• Academic & Industrial R&D: A valuable reagent for chemical research focused on stereochemistry, medicinal chemistry, and process development.

Basic Information

Product Name	(S)-o-Isopropylidene Glycerol Mesylate
CAS No.	90129-42-3
Molecular Formula	C7H14O5S
Molecular Weight	210.25 g/mol
Synonyms	(S)-(-)-1,2-O-Isopropylidene-3-O-methanesulfonylglycerol; (S)-(-)-1,2-O-Isopropylideneglycerol 3-methanesulfonate; (S)-(-)-1,2-Isopropylidene Glyceryl Methanesulfonate; (S)-(-)-1,2-O-Isopropylidene-3-O-mesylglycerol; (S)-(-)-1,2-O-Isopropylidene-3-O-tosylglycerol (common misnomer); (S)-(-)-Solketal Mesylate; (S)-(-)-Acetonide Glycerol Mesylate; (S)-Glycerol Acetonide Mesylate
EINECS	Contact for details

Quality Control

Our (S)-o-Isopropylidene Glycerol Mesylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.