Description

Rebamipide is a synthetic amino acid derivative and a gastroprotective agent with a unique mechanism of action. It is a critical active pharmaceutical ingredient (API) valued for its ability to promote mucosal defense and accelerate the healing of gastric ulcers. This compound is essential for pharmaceutical manufacturers developing treatments for gastritis, gastric ulcers, and other gastrointestinal disorders. Our supply of Rebamipide CAS NO 90098-04-7 ensures high purity and reliable quality for global pharmaceutical production.

Application

The primary and well-established application of Rebamipide is in the pharmaceutical industry. Its specific uses include:

• Active Pharmaceutical Ingredient (API): Core component in prescription medications for the treatment and prevention of gastric ulcers and gastritis.
• Mucosal Defense Formulations: Used in drugs designed to enhance gastric mucus secretion and protect the stomach lining from irritants.
• Anti-inflammatory Gastrointestinal Therapies: Incorporated into treatments that address inflammation associated with conditions like chronic gastritis.
• Drug Development & Research: Serves as a reference standard and key intermediate in preclinical and clinical research for new gastroenterology drugs.
• Combination Therapies: May be formulated with other agents, such as proton pump inhibitors, for comprehensive ulcer management.

Basic Information

Product Name	Rebamipide
CAS No.	90098-04-7
Molecular Formula	C19H15ClN2O4
Molecular Weight	370.79 g/mol
Synonyms	2-(4-Chlorobenzamido)-3-[2(1H)-quinolinon-4-yl]propionic acid; OPC-12759; Rebamipidum; Gastrom; Mucosta; Proamipide
EINECS	Contact for details

Quality Control

Our Rebamipide is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols include identity confirmation, purity analysis, and control of specified impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results from tests such as HPLC assay, related substances, residual solvents, and heavy metals. Our quality system is designed to support compliance with GMP, ICH Q7, and other relevant regulatory guidelines for API production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Water (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.