Description

Magaldrate is a high-purity, layered double hydroxide antacid compound, also known as a hydrotalcite-like substance. Its unique structure provides a high acid-neutralizing capacity and sustained buffering action, making it a critical active pharmaceutical ingredient (API) for gastrointestinal therapeutics. This product is essential for manufacturers in the pharmaceutical and nutraceutical industries requiring a reliable and effective antacid component. Magaldrate CAS NO 1317-26-6 is supplied under stringent quality control to ensure batch-to-batch consistency for formulation stability.

Application

• Pharmaceutical Antacid Formulations: Primary use as the active ingredient in chewable tablets, suspensions, and gels for the treatment of heartburn, acid indigestion, and gastroesophageal reflux disease (GERD).
• Combination Drug Products: Used in combination with simethicone (anti-foaming agent) or alginates in over-the-counter (OTC) medications for enhanced symptomatic relief.
• Veterinary Pharmaceuticals: Incorporated into antacid preparations for domestic animals and livestock to manage gastric hyperacidity.
• Nutraceutical and Dietary Supplements: Serves as a buffering agent in supplement formulations designed to support digestive health.
• Research & Development: Utilized in chemical and pharmacological research as a model layered double hydroxide material and for studying gastric acid neutralization kinetics.

Basic Information

Item	Details
Product Name	Magaldrate
CAS No.	1317-26-6
Molecular Formula	Al5Mg10(OH)31(CO3)2·nH2O
Molecular Weight	Contact for details (variable hydrate)
Synonyms	Magaldrate; Dihydroxyaluminum Magnesium Carbonate Monohydrate; Aluminum Magnesium Hydroxide Carbonate Hydrate; Hydrotalcite (pharmaceutical grade); L-APM 05; Magaldratum; Gastrogel; Monalium Hydrate; Antacid No. 5; Almax
EINECS	215-290-1

Quality Control

Our Magaldrate is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance protocols are designed to ensure compliance with relevant pharmacopoeial monographs, including USP-NF and Ph. Eur. specifications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as identification, assay, acid-neutralizing capacity, and impurity profiles. We maintain a cGMP-aligned quality management system to guarantee supply reliability and product integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, the product must be stored in a cool, dry place with controlled humidity. Recommended storage temperature is between 15°C and 25°C. Keep the container tightly sealed after each use to minimize moisture absorption, which can affect flow properties and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Assay (Al2O3 & MgO)	Meet pharmacopoeial requirements
Acid Neutralizing Capacity	≥ 25.0 mEq/g
Loss on Drying	≤ 20.0 %
Chloride	≤ 0.1 %
Sulfate	≤ 0.5 %
Arsenic (As)	≤ 3 ppm
Heavy Metals (as Pb)	≤ 20 ppm
Microbial Limits	Meet Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.