Description

2,2-Dimethyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride is a high-purity organic salt, recognized as a valuable chiral amine building block in advanced synthesis. Its core value proposition lies in providing a rigid, substituted tetrahydropyran scaffold, which is crucial for modulating the physicochemical properties and biological activity of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the construction of novel herbicides, fungicides, and insecticides, where its structural motif can enhance stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	2,2-Dimethyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride
CAS No.	90048-31-0
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	4-Amino-2,2-dimethyltetrahydropyran hydrochloride; 2,2-Dimethyl-4-aminotetrahydropyran hydrochloride; 4-Amino-2,2-dimethyl-3,4,5,6-tetrahydro-2H-pyran hydrochloride; 2,2-Dimethyltetrahydro-2H-pyran-4-amine hydrochloride; 4-Pyranamine, tetrahydro-2,2-dimethyl-, hydrochloride; 2,2-Dimethyl-4-aminotetrahydropyran HCl
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-Tetrahydro-Pyran-4-Ylamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.