Description

4-Bromo-1,5-Naphthyridine is a versatile and high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in the development of pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive bromine site for further functionalization.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to the naphthyridine core's electron-accepting properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig) to form carbon-carbon and carbon-heteroatom bonds.

Basic Information

Product Name	4-Bromo-1,5-Naphthyridine
CAS No.	90001-34-6
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	1,5-Naphthyridine, 4-bromo-; 4-Bromo-1,5-naphthyridine; 4-Bromonaphthyridine; 4-Bromo[1,5]naphthyridine; 4-Bromo-1,5-diazanaphthalene; NSC 406901; 90001-34-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,5-Naphthyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.