Description

Keratan Sulfate is a linear, sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units of galactose and N-acetylglucosamine. This compound is a critical structural and functional component of the extracellular matrix, particularly in cartilage, cornea, and bone, where it plays a vital role in tissue hydration, resilience, and cellular signaling. It is essential for research and development in the life sciences, serving as a key material for studying connective tissue disorders, developing biomaterials, and formulating advanced nutraceuticals and cosmeceuticals.

Application

• Biomedical Research: Used as a standard or substrate in studies of osteoarthritis, corneal dystrophy, and other connective tissue diseases to understand GAG metabolism and pathology.
• Pharmaceutical Development: Investigated as a potential active ingredient or excipient in drug delivery systems, viscosupplementation therapies, and wound healing formulations.
• Nutraceuticals: Incorporated into dietary supplements targeting joint health and cartilage support, often in combination with other GAGs like chondroitin sulfate.
• Cosmeceuticals: Utilized in high-end skincare products for its purported hydrating and skin-repairing properties, helping to improve skin texture and elasticity.
• Biomaterial Engineering: Serves as a component in hydrogels and scaffolds for tissue engineering applications, particularly for cartilage and corneal repair.
• Diagnostic Reagents: Employed in the development of ELISA kits and other assays for the detection and quantification of GAGs in biological samples.

Basic Information

Product Name	Keratan Sulfate
CAS No.	9056-36-4
Molecular Formula	(C14H21NO14S)n
Molecular Weight	Variable polymer
Synonyms	Keratan Sulfate I; Keratan Sulfate II; Keratosulfate; KS; Keratan Polysulfate; Corneal Keratan Sulfate; Skeletal Keratan Sulfate; KSPG (Keratan Sulfate Proteoglycan); (1->3)-O-β-D-Galactopyranosyl-(1->4)-2-acetamido-2-deoxy-6-O-sulfo-β-D-glucopyranan
EINECS	Contact for details

Quality Control

Our Keratan Sulfate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) detailing specifications such as sulfate content, molecular weight distribution, and purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to humidity or light may degrade the material. For long-term stability, consider storage under desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (as dry basis)	≥ 90% (by weight)
Sulfate Content	15 - 25%
Protein Content	≤ 5%
Loss on Drying	≤ 10.0%
Residue on Ignition	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Microbial Limits	Meets standard requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.