Description

8-Phenyltheophylline is a xanthine derivative and a potent, selective adenosine receptor antagonist. This compound matters as a critical research chemical and pharmaceutical intermediate, offering high purity and structural specificity for advanced studies. It is primarily needed by researchers in pharmacology and medicinal chemistry, as well as by manufacturers developing targeted therapeutic agents for conditions related to adenosine signaling pathways.

Application

• Pharmacological Research: Used as a selective antagonist for adenosine A1 and A2A receptor studies in vitro and in vivo.
• Medicinal Chemistry: Serves as a key intermediate or reference standard in the synthesis of novel xanthine-based drug candidates.
• Biochemical Assay Development: Employed as a tool compound to validate assays targeting purinergic signaling pathways.
• Neuroscience Research: Investigated for its effects on neurotransmitter release and neuroprotection in preclinical models.
• Cardiovascular Research: Utilized to study the role of adenosine receptors in heart rate, coronary flow, and ischemic preconditioning.
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	8-Phenyltheophylline
CAS No.	961-45-5
Molecular Formula	C15H14N4O2
Molecular Weight	282.30 g/mol
Synonyms	8-Phenyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-Phenyl-1,3-dimethylxanthine; 1,3-Dimethyl-8-phenylxanthine; 8-Phenyltheophylline; 8-PT; 8-Phenyl-1,3-dimethyl-7H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 8-Phenyltheophylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.