Description

1H-Spiro[Cyclohexane-1,2-Quinazolin]-4(3H)-One is a high-purity, spirocyclic quinazolinone derivative, a specialized heterocyclic compound of significant interest in advanced organic synthesis. Its unique fused ring structure makes it a valuable and versatile pharmacophore and synthetic intermediate for research and development. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Employed in the construction of complex spirocyclic and polycyclic heterocyclic systems.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	1H-Spiro[Cyclohexane-1,2-Quinazolin]-4(3H)-One
CAS No.	950-31-2
Molecular Formula	C₁₃H₁₄N₂O
Molecular Weight	214.26 g/mol
Synonyms	1H-Spiro[cyclohexane-1,2'-quinazolin]-4'(3'H)-one; Spiro[cyclohexane-1,2-quinazolin]-4(3H)-one; 1'H-Spiro[cyclohexane-1,2'-quinazolin]-4'(3'H)-one; 1H-Spiro(cyclohexane-1,2'-quinazolin)-4'(3'H)-one; Quinazolin-4(3H)-one, 1,2-dihydro-2-spirocyclohexane-; 2-Spirocyclohexane-1,2-dihydroquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 1H-Spiro[Cyclohexane-1,2-Quinazolin]-4(3H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.