Description

4-(2-Bromo-Acetyl)-Benzenesulfonamide is a versatile and high-purity bromoacetyl sulfonamide derivative, serving as a critical building block in advanced organic synthesis. Its reactive bromoacetyl group makes it an essential intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide moiety acts as a pharmacophore.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides that incorporate sulfonamide functional groups for enhanced biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for affinity-based protein profiling and the development of activity-based probes due to its electrophilic bromoacetyl group.
• Material Science Research: Employed in the synthesis of specialized polymers and functionalized surfaces where the sulfonamide group imparts specific chemical or physical properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(2-Bromo-Acetyl)-Benzenesulfonamide
CAS No.	944-33-2
Molecular Formula	C8H8BrNO3S
Molecular Weight	278.12 g/mol
Synonyms	p-(Bromoacetyl)benzenesulfonamide; 4-(Bromoacetyl)benzenesulfonamide; 1-(4-Sulfamoylphenyl)-2-bromoethanone; 2-Bromo-1-[4-(aminosulfonyl)phenyl]ethanone; α-Bromo-4-sulfamoylacetophenone; N-(4-Bromoacetylphenyl)sulfonamide; Benzenesulfonamide, 4-(2-bromoacetyl)-; 4-(2-Bromoacetyl)benzene-1-sulfonamide
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Bromo-Acetyl)-Benzenesulfonamide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.