Description

1-Cyano-1,2-Dihydro-2-Hydroxyquinoline is a versatile heterocyclic building block and key synthetic intermediate in advanced organic chemistry. Its unique fused quinoline structure, functionalized with cyano and hydroxyl groups, makes it a valuable precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides that leverage the quinoline scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and photostable compounds for advanced materials.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cyclization and functional group transformation reactions.

Basic Information

Product Name	1-Cyano-1,2-Dihydro-2-Hydroxyquinoline
CAS No.	941-87-7
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	2-Hydroxy-1,2-dihydro-1-quinolinecarbonitrile; 1-Cyano-2-hydroxy-1,2-dihydroquinoline; 1,2-Dihydro-2-hydroxy-1-quinolinecarbonitrile; 2-Hydroxy-1-cyano-1,2-dihydroquinoline; Quinoline, 1-cyano-1,2-dihydro-2-hydroxy-; 1-Cyano-2-hydroxy-1,2-dihydroquinoline; 1-Quinolinecarbonitrile, 1,2-dihydro-2-hydroxy-
EINECS	Contact for details

Quality Control

Our 1-Cyano-1,2-Dihydro-2-Hydroxyquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.