Description

2-Bromo-1-(Bromomethyl)-4-Nitrobenzene is a versatile and highly functionalized aromatic compound, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of reactive bromine and nitro groups, enabling precise chemical transformations for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, reliable starting materials for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring substituted benzene cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the nitro and bromomethyl groups facilitate further functionalization.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The bromine substituents make it a suitable substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Nucleophilic Substitution Scaffold: The bromomethyl group is highly reactive towards nucleophiles, allowing for the introduction of various functional groups (e.g., amines, thiols).

Basic Information

Product Name	2-Bromo-1-(Bromomethyl)-4-Nitrobenzene
CAS No.	940-05-6
Molecular Formula	C7H5Br2NO2
Molecular Weight	294.93 g/mol
Synonyms	1,2-Dibromo-4-Nitrotoluene; 2-Bromo-α-bromo-4-nitrotoluene; 4-Nitro-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-4-nitrobenzene; NSC 404087; α,2-Dibromo-4-nitrotoluene; 4-Nitro-o-xylylene dibromide
EINECS	213-363-3

Quality Control

Our 2-Bromo-1-(Bromomethyl)-4-Nitrobenzene is produced under a stringent quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the exacting standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.