Description

3-Bromoquinolin-2(1H)-One is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its ability to serve as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for innovative R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the quinoline scaffold offers unique biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Functional Dye Development: Acts as a core structure in the synthesis of specialized dyes and fluorescent markers.

Basic Information

Product Name	3-Bromoquinolin-2(1H)-One
CAS No.	939-16-2
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	3-Bromocarbostyril; 3-Bromo-2-hydroxyquinoline; 3-Bromo-1H-quinolin-2-one; 2-Hydroxy-3-bromoquinoline; 3-Bromoquinolin-2-ol; 3-Bromo-2(1H)-quinolinone; 3-Bromocarbostyrile; 3-Brom-2(1H)-chinolon
EINECS	Contact for details

Quality Control

Our 3-Bromoquinolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with standard specifications typically meeting or exceeding 98% purity (by HPLC). Each batch is accompanied by a detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.