Description

2H-1-Benzopyran-2-One, 4-Bromo- is a brominated derivative of coumarin, a versatile heterocyclic scaffold. This compound serves as a critical synthetic intermediate and building block in advanced organic chemistry and materials science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or possessing fluorescent properties.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging the bioactivity of the coumarin core.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions, nucleophilic substitutions, or cyclizations.
• Material Science: Investigated as a component in the development of organic light-emitting diodes (OLEDs), sensors, and photochromic materials due to its optical properties.
• Fluorescent Probe Development: Utilized in creating molecular probes and markers for biochemical and diagnostic applications.
• Fragrance & Dye Intermediate: Acts as a starting material for synthesizing specialized coumarin-based dyes and fragrance compounds.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 4-Bromo-
CAS No.	938-40-9
Molecular Formula	C9H5BrO2
Molecular Weight	225.04 g/mol
Synonyms	4-Bromocoumarin; 4-Bromo-2H-chromen-2-one; 4-Bromo-1-benzopyran-2-one; 4-Bromo-2H-1-benzopyran-2-one; 4-Brom-2-oxo-chromen; NSC 2215; 4-Bromo-2-oxo-2H-chromene
EINECS	213-342-6

Quality Control

Our 2H-1-Benzopyran-2-One, 4-Bromo- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.