Description

4-Bromoquinolin-2(1H)-One is a versatile brominated quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its ability to act as a key building block for constructing complex heterocyclic frameworks, enabling the development of novel compounds with targeted properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential anticancer, antiviral, and antimicrobial agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core structure.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized quinoline motifs into more complex molecules.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new reaction pathways involving halogenated heterocycles.

Basic Information

Product Name	4-Bromoquinolin-2(1H)-One
CAS No.	938-39-6
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	4-Bromo-2-hydroxyquinoline; 4-Bromo-2-quinolinol; 4-Bromo-1H-quinolin-2-one; 2-Hydroxy-4-bromoquinoline; 4-Bromocarbostyril; 938-39-6; 4-Bromoquinolin-2-ol; 4-Bromo-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 4-Bromoquinolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assay and identification by FT-IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.