Description

[1R-(1Alpha,3Beta,5Beta,7Alpha)]-3,8,8-Trimethyl-4-Oxatricyclo[5.1.0.03,5]Octane is a high-purity, specialized bicyclic ether compound with a unique and rigid molecular architecture. This structure makes it a valuable chiral building block and intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control. Our supply is characterized by consistent quality and reliable availability to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides with specific stereochemical properties for enhanced efficacy.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials where its unique oxatricyclic structure is required.
• Asymmetric Catalysis Research: Acts as a ligand precursor or a test substrate in the development of new asymmetric catalytic reactions and methodologies.
• Academic & Industrial R&D: Utilized in organic chemistry research for studying reaction mechanisms, natural product synthesis, and the development of new synthetic routes.

Basic Information

Item	Detail
Product Name	[1R-(1Alpha,3Beta,5Beta,7Alpha)]-3,8,8-Trimethyl-4-Oxatricyclo[5.1.0.03,5]Octane
CAS No.	936-92-5
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(1R,3S,5R,7S)-3,8,8-Trimethyl-4-oxatricyclo[5.1.0.0³,⁵]octane; (-)-α-Santonin derivative; 1R,3S,5R,7S-3,8,8-Trimethyl-4-oxatricyclo[5.1.0.0³,⁵]octane; 4-Oxatricyclo[5.1.0.0³,⁵]octane, 3,8,8-trimethyl-, (1R,3S,5R,7S)-; Santonin related compound
EINECS	Contact for details

Quality Control

Every batch of [1R-(1Alpha,3Beta,5Beta,7Alpha)]-3,8,8-Trimethyl-4-Oxatricyclo[5.1.0.03,5]Octane undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity (by GC/HPLC), chiral purity, and other critical parameters is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.