Description

Sodium Thiophenoxide is an organosulfur compound and the sodium salt of thiophenol, serving as a versatile and highly reactive nucleophile and building block in organic synthesis. Its primary value lies in its ability to efficiently introduce the thiophenoxy (PhS-) group into target molecules, enabling the synthesis of complex sulfur-containing intermediates. This chemical is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical producers engaged in creating novel compounds, ligands, and functional materials.

Application

• Pharmaceutical Intermediates: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing aryl sulfide or disulfide linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the thiophenoxy moiety contributes to biological activity.
• Polymer & Material Science: Acts as a chain transfer agent or modifier in polymerization reactions and in the surface functionalization of nanomaterials.
• Organic Synthesis Reagent: Employed in nucleophilic aromatic substitution (SNAr), addition reactions, and as a precursor for other organosulfur compounds like sulfides and sulfones.
• Ligand Preparation: Useful for synthesizing sulfur-based ligands used in coordination chemistry and catalysis.
• Cross-Coupling Reactions: Serves as a coupling partner in transition-metal catalyzed reactions, such as with palladium catalysts.

Basic Information

Product Name	Sodium Thiophenoxide
CAS No.	930-69-8
Molecular Formula	C6H5NaS
Molecular Weight	116.16 g/mol
Synonyms	Sodium Benzenethiolate; Sodium Phenylmercaptide; Thiophenol Sodium Salt; Benzenethiol, Sodium Salt; Phenyl Sodium Sulfide; Sodium Thiophenolate; Sodium Phenysulfide; Phenythiol Sodium Salt
EINECS	213-232-6

Quality Control

Our Sodium Thiophenoxide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to handle and store under an inert atmosphere (e.g., nitrogen or argon) to maintain purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to pale yellow powder or crystalline solid
Identification (IR)	Conforms
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.