Description

Sodium 2-Methyl-2-Propanethiolate is the sodium salt of tert-butyl mercaptan, a versatile organosulfur reagent. This compound is valued for its role as a powerful nucleophile and base, enabling critical carbon-sulfur bond formation and deprotonation reactions in synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the tert-butylthio group into active pharmaceutical ingredients (APIs) and advanced intermediates.
• Ligand and Catalyst Preparation: Used in the synthesis of sulfur-containing ligands for transition metal catalysis and organocatalysts.
• Polymer Modification: Employed as a chain-transfer agent or functionalization reagent in the production of specialty polymers and materials.
• Agrochemical Production: Facilitates the synthesis of sulfur-containing herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Reagent: Acts as a strong base for deprotonation and as a nucleophile in substitution and addition reactions to construct complex organic frameworks.
• Flavor and Fragrance Industry: Used in the controlled synthesis of specific sulfur-containing compounds that contribute to aroma profiles.

Basic Information

Product Name	Sodium 2-Methyl-2-Propanethiolate
CAS No.	29364-29-2
Molecular Formula	C4H9NaS
Molecular Weight	112.17 g/mol
Synonyms	Sodium tert-Butylthiolate; Sodium tert-Butyl Mercaptide; tert-Butylsodium Sulfide; 2-Methyl-2-propanethiol, sodium salt; Sodium tert-Butanethiolate; Sodium t-Butylthiolate; tert-C4H9SNa
EINECS	Contact for details

Quality Control

Our Sodium 2-Methyl-2-Propanethiolate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed and opened only under controlled, moisture-free conditions. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or lumps
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Solubility Test	Soluble in THF, DMF; reacts with water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.